The course takes place on Tuesdays, 15:15-17:00, lecture hall: tba

Reading material

The course builds on the Systems Biology book ​by Uri Alon, which is highly recommended.

Recommended further study material:

online courses covering related topics:

Uri Alon: Systems Biology

Jeff Gore: MIT open courseware

For more advanced studies of dynamical systems read Steven Strogatz' s book and lecture.

The booklet "Optima for animals" by R. McNeill Alexander provides a beautiful introduction to optimality principles in animal development and behaviour.er

20.9. Introduction

27.9. Negative and positive feedback

4.10. feed forward loops

11.10. no lecture

18. 10. design principles in cellular signalling

25. 10. Toggle Switch and bi-stability

1.11. Oscillations and body size control

8.11. multi cellular dynamics

15.11. cell size and transcription

22.11. trade-offs and optimality

29.11. fitness landscapes

6.12. theory of aging

13.12. synthetic biology

20.12. Q&A, recap


- There will be a written exam at the end of the semester.

- 5 out of 6 home work assignments must be completed and handed-in on time


Assignments are due on Tueday, 15.00, two weeks after the respective lecture.

Submit them by email to: systemsbiology2021[at]gmail.com or drop them in my post box in Baltzerstrasse 4.

Proven effort to solve 5 out of 6 assignments correctly is required to pass the course.

There will be a Q&A session with our TA Aaditya Saxena via google meet in the weeks before assignment deadlines.